15/12/2020
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(Gr. Chromos; color: Soma; body) in eukaryotes; a linear thread like structure composed of the DNA and protein, found in the nucleus of the cell. It contain genes; carry genes from parent cell to daughter cells. (Absorb dark stain).
chromosome is circular thread (Strand) composed of solely of DNA.
: A very long fiber of protein and DNA which is loosely coiled and dispersed state of chromosome become chromosomes during cell division, (where tightly coiled or condensed)
: the number of chromosomes varies from species to species (from 2 to 500 pairs) e.g; in human (46),monkey (48), mucor(2), penicillium (2 haploid), drosophila (8), mouse (40), mosquito (6), honey bee (32), rice (24), onion (16), Garden pea (14), Corn (20), sugar cane (80), yeast (18), Neurospora (7 haploid) etc.
: (1) Hofmeister (1848) observed thread like structures in the nuclei of pollen mother cells of Tradescantia. (A plant)
(2) Walther Flemming (1882): German embryologist, observed these thread in a dividing cells of Salamander larvae (Amphibians)
(3) Waldyer (1888): designated these thread, the chromosomes (Chromes, color, soma; body) because they were darkly stained.
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The chromosomes can be best studied (seen) during metaphase of mitosis.
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Primary Constriction: divide the chromosome in to two arms.
: in the region of primary constriction lies Centromere.
: each chromosome consist of two chromatids which are attached by Centromere (called sister chromatids).
: around the Centromere a disc shaped protein to which spindle fibers get attached during cell division.
: in some chromosome, another constriction called secondary constriction and the part of chromosome beyond it is called satellite DNA. (later become nucleus)
: the tips of the chromosomes are round and sealed